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Hypogenica logohypogenica

Pure calcium carbonate, made carbon negative.

Our biotechnology leverages a novel bacterial metabolism to make pure calcium carbonate that is cleaner, cheaper, and more efficient. How? Using cave science.

01/03

We explore microbial ecosystems deep within Alabama's 4,000+ caves, where bacteria have precipitated minerals in the dark for millennia.

Turning cave chemistry into an engine of carbon negative materials.

We combine microbiology, geology, and materials science to produce calcium carbonate the way nature does, at industrial scale.

Microbiology

Cave science

Microbial ecosystems from Alabama's caves, directing biomineralization with precision.

A researcher sampling at a still cave pool among stalactites
Bioprocess

Biomineralization

A bacterial process that manufactures pure CaCO3 from atmospheric CO2, in bioreactors that scale by adding tanks.

An amber bacterial culture in a laboratory bioreactor
Sequestration

Carbon capture

Every batch sequesters carbon, creating a carbon negative supply of industrial calcite.

Microscopy of precipitated calcium carbonate crystals

There are three ways to make calcium carbonate.

Two of them start by digging up limestone. Ours starts with the carbon already in the air. That is what makes mPCC carbon negative, and what lets us control the crystal and build the plant wherever the customer is.

GCC

Mined

Feedstock
Limestone cut out of a quarry
Process
Blasted, crushed, then ground down to size
Particle control
Limited. The shape and the spread are whatever the mill leaves behind
GHG footprint
Emissive. Quarrying, hauling and grinding all burn energy
Where it can be built
Wherever the deposit happens to be
PCC

Conventional

Feedstock
Limestone again, burned to lime first
Process
Kiln, then slaking, then recarbonation
Particle control
Good. Set by the chemistry in the reactor
GHG footprint
Emissive. Burning the limestone releases CO2 before any of it is recaptured
Where it can be built
Beside a kiln, usually on the site of a paper mill
Microbially precipitated

Our mPCC

Feedstock
Atmospheric CO2, captured by bacteria
Process
Bacteria precipitate calcite the way they do underground, at ambient conditions
Particle control
Set biologically. The organism decides the crystal, so size and morphology are dialled in
GHG footprint
Carbon negative. Every gram locks CO2 away instead of releasing it
Where it can be built
Modular bioreactors, sited next to the customer

Who buys calcium carbonate, and what they do with it.

It goes into more than most people expect. Paint is where we start, since that is the application the NSF is funding. The rest of this list is where the same material already goes.

  • Paint and coatings

    An extender that carries opacity, so a formulation needs less titanium dioxide. Particle size sets the sheen and the way the paint flows.

  • Plastics

    Filler in PVC pipe and profile, polyolefin film and masterbatch. It adds stiffness and dimensional stability while displacing resin.

  • Paper

    Filler and coating pigment. It brings brightness, opacity and a printable surface at a lower cost than fibre.

  • Cosmetics

    Bulking and oil absorption in pressed powders and foundations, and a mild abrasive in toothpaste.

  • Drug delivery

    An antacid and calcium source in its own right, a tablet excipient, and a carrier for controlled release, where purity and particle size govern the dose.

  • Adhesives and sealants

    A reinforcing filler in caulks, sealants and rubber that controls viscosity and stops a bead from slumping.

  • Food and supplements

    Calcium fortification, anti-caking and acidity regulation, at food grade purity.

  • Construction and agriculture

    An additive in cements, mortars and joint compounds, and a soil amendment that lifts pH on acidic ground.

Experts in technical applications of cave and materials science.

Led by experts in cave microbiology and materials science, with research roots at the University of Alabama.

Reilly Blackwell

Reilly Blackwell

Founder & CEO

George Breley

George Breley

Co-Founder

Dr. Hazel Barton

Dr. Hazel Barton

CTO · Cave Microbiologist

Making a cleaner, cost effective calcium carbonate, for us all.

It's not just millions of dollars saved. It's also preserving the future of our planet and its critical ecosystems. As scientists and cavers, we're invested in a world where industry and environment work together.

Carbon negative

Every gram sequesters CO2

Millions saved

Lower cost production at scale

Pure CaCO3

Industrial grade calcite

A caver examining white mineral formations on a cave wall

Get in touch

info@hypogenica.com

Tuscaloosa, Alabama

A caver rappelling into a limestone cave